Dr. med. Dirk Manski



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Molluscum Contagiosum

Definition

Molluscum contagiosum is a viral infection of the epidermis with pearly papules (CDC Guidelines, 2006).

Epidemiology of Molluscum Contagiosum

Risk groups for molluscum contagiosum: children and adolescents, sports with skin-to-skin contact, sexually active persons, patients with immune deficiency.

Etiology of Molluscum Contagiosum

Molluscum contagiosum virus (MCV):

DNA virus of the pox group. Incubation period 2–7 weeks. Transmission from human to human via skin-to-skin contact or via inanimate vectors (e.g. towels).

Signs and Symptoms

Diagnosis

Diagnosis is possible with inspection only, biopsy is necessary for untypical lesions (virus-infected cells with DNA-containing inclusion bodies).

Treatment of Molluscum Contagiosum

Natural course:

Usually self-limiting disease, which lasts several months to two years. This justifies observation without active therapy. Widespread and persistent disease is possible in patients with immunodeficiency (HIV).

Topical therapy:

Local application of cantharidin, imiquimod, podophyllotoxin and numerous other substances have been effectively used against molluscum contagiosum. Disadvantages include side effects and high cost.

Surgical therapy:

Curettage followed by iodine-containing disinfection. Alternative techniques: cryosurgery or laser coagulation. Disadvantages include pain and scarring.







Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z



References

Bikowski 2004 BIKOWSKI, Jr.:
Molluscum contagiosum: the need for physician intervention and new treatment options.
In: Cutis
73 (2004), Nr. 3, S. 202–6

Center for Disease Control and Prevention.:
Sexually transmitted diseases treatment guidelines 2006.
in: MMWR
2006; 55 (No. RR-11): 1–93.


Smith und Skelton 2002 SMITH, K. J. ; SKELTON, H.:
Molluscum contagiosum: recent advances in pathogenic mechanisms, and new therapies.
In: Am J Clin Dermatol
3 (2002), Nr. 8, S. 535–45

Ting und Dytoc 2004 TING, P. T. ; DYTOC, M. T.:
Therapy of external anogenital warts and molluscum contagiosum: a literature review.
In: Dermatol Ther
17 (2004), Nr. 1, S. 68–101

Tyring 2003 TYRING, S. K.:
Molluscum contagiosum: the importance of early diagnosis and treatment.
In: Am J Obstet Gynecol
189 (2003), Nr. 3 Suppl, S. S12–6


  Deutsche Version: Molluscum contagiosum: virale Infektion der Haut.