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C-Reactive Protein (CRP) – Serum Blood Test

The C-reactive protein is a classic acute phase protein and part of the immune system. CRP is synthesized in the liver, binds to dying cells or some bacteria and activates the complement system.

Standard value:

<5 mg/l.

Laboratory test method:

Exact measurement with immunoturbidimetry (see cystatin C) or ELISA. Semiquantitative measurement with latex agglutination test.

Indications:

Diagnosis and treatment monitoring of inflammatory diseases, after operations, tumor prognosis parameter.

Differential Diagnosis of Elevated CRP

Reliable and significant increase in bacterial infections (faster than fever or leukocytosis), less pronounced in viral infections
Advanced malignant tumors
Tissue trauma
Rheumatic diseases
After surgery, CRP increases within 6 h until the 3rd postoperative day. Without infection or complications, CRP decreases with the 4th postoperative day and reaches (near) normal values around the 7th to 10th postoperative day.

Urea blood test

Index

Erythrocyte sedimentation rate

Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

References

Guder, W. G. & Nolte, J. Das Laborbuch für Klinik und Praxis
Urban + Fischer, 2009

Siegenthaler 1988 SIEGENTHALER, W. ; SIEGENTHALER, W. (Hrsg.): Differentialdiagnose innerer Krankheiten.
Georg Thieme Verlag, Stuttgart, New York., 1988

Deutsche Version: CRP im Serum

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